Olive oil being poured on a spoon with a piece of olive.

Olive Oil and Dementia: Can This Healthy Fat Protect Your Brain?

Written by: Dr James Pendleton

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Published

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Time to read 12 min

Olive oil and dementia have been closely studied, with research suggesting that olive oil consumption may support brain health and reduce the risk of dementia-related death. A follow-up study from the Nurses’ Health Study found that consuming olive oil daily—about half a tablespoon—was associated with a lower risk of fatal dementia than other vegetable oils and commercial mayonnaise.


Rich in monounsaturated fatty acids and antioxidant compounds like vitamin E, extra virgin olive oil may help protect cognitive health by supporting heart health, benefiting cardiovascular health, and strengthening the blood-brain barrier. This article explores the potential benefits of olive oil intake, its connection to dementia risk, and how to incorporate it into a healthy diet.

What Is Dementia and Why Is Brain Health Important?

Dementia is a progressive neurological disorder that impairs memory, cognitive function, and daily activities. It develops due to brain cell damage, which leads to cognitive decline and, in some cases, dementia-related mortality. A healthy diet, including olive oil intake, is key in supporting cognitive-related health and lowering the risk of dementia.


Types of Dementia and Symptoms


  • Alzheimer’s disease – The most common type, causing memory loss and confusion due to plaque buildup in the brain.

  • Vascular dementia – Linked to cardiovascular disease and poor blood flow to the brain, affecting cognitive health.

  • Lewy body dementia – Involves protein deposits in nerve cells, leading to hallucinations and movement difficulties.

  • Frontotemporal dementia – Affects behavior and personality due to nerve cell loss in the brain’s frontal and temporal lobes.

Key Factors That Impact Dementia Risk

Dementia risk is influenced by multiple factors, including genetics, diet, and lifestyle. While some risk factors, such as age and family history, cannot be changed, adopting a healthy diet and lifestyle can support brain health and lower the risk of dementia-related deaths.


Genetics, Diet, and Lifestyle Factors


  • Genetics – A family history of dementia can increase the likelihood of developing cognitive impairment.

  • Diet – Following dietary guidelines emphasizing extra virgin olive oil, monounsaturated fats, and antioxidant compounds may reduce dementia-related mortality.

  • Lifestyle – Regular physical activity, cognitive engagement, and social interaction help maintain brain function.

  • Cardiovascular health – Supporting heart health through a healthy diet and daily olive oil consumption can improve blood flow to the brain.

  • Environmental factors – Exposure to air pollution and toxins may contribute to cognitive decline.

"Olive oil contains powerful compounds that protect brain health and may lower the risk of dementia-related death.”

The Link Between Olive Oil and Dementia Prevention

Studies have observed an association between olive oil consumption and a lower risk of dementia-related death. Studies suggest that consuming olive oil daily may benefit cognitive health and protect the brain from neurodegeneration.

Overview of Research on Olive Oil and Dementia

The Nurses’ Health Study and a follow-up study published in JAMA Network Open found that higher olive oil consumption was associated with a lower risk of fatal dementia. Participants who consumed about half a tablespoon of olive oil daily had a lower risk of dementia-related mortality than those who used other vegetable oils or commercial mayonnaise.


These findings suggest that olive oil intake may contribute to brain health and cognitive function by reducing inflammation, supporting cardiovascular health, and protecting against oxidative stress.

How Olive Oil May Protect the Brain from Cognitive Decline

Olive oil contains monounsaturated fatty acids and antioxidant compounds, which may help support brain cell function. The polyphenols in extra virgin olive oil may strengthen the blood-brain barrier, reducing the buildup of harmful proteins linked to dementia risk. Additionally, benefiting cardiovascular health through a diet rich in olive oil supports healthy blood flow to the brain, which is essential for cognitive-related health.

Harvard’s Research on Olive Oil and Dementia Mortality

A study from the Harvard T.H. Chan School of Public Health found that individuals with higher daily olive oil consumption had a lower risk of death from dementia compared to those who consumed other oils. The research associate leading the study noted that dietary habits, particularly replacing unhealthy fats with olive oil, could improve diet quality and support heart health. Since cardiovascular disease is a key risk factor for dementia, incorporating olive oil into a Mediterranean diet may have long-term benefits for brain function and public health.

Glass of olive oil poured into a bowl with fresh olives.

How Olive Oil Benefits Brain Health

Olive oil contains powerful compounds that protect brain health and may lower the risk of dementia-related death. Its antioxidant, anti-inflammatory, and heart-supporting properties contribute to improved cognition and long-term brain function.

Antioxidant Properties That Support Brain Health

Polyphenols in extra virgin olive oil have antioxidant properties that may help reduce oxidative stress, a factor in cognitive decline. These antioxidant compounds neutralize free radicals that can damage neurons and contribute to dementia risk.


Research suggests that polyphenols may slow the progression of cognitive-related health issues by reducing the buildup of harmful proteins in the brain. Higher olive oil intake has been linked to improved diet quality and a lower risk of dementia-related deaths, making it a valuable part of a brain-supporting diet.

Anti-Inflammatory Effects of Olive Oil

Chronic inflammation in the brain is linked to neurodegenerative diseases and dementia risk. Olive oil contains natural anti-inflammatory compounds that may reduce brain inflammation and support cognitive function.


Studies suggest that consuming olive oil daily may help reduce inflammation, which is linked to neurodegeneration. Its potential benefits include improved memory, better neuronal communication, and a lower risk of fatal dementia. These effects contribute to the protective role of olive oil in brain health.

Monounsaturated Fats and Blood Flow

Monounsaturated fats in olive oil play a key role in maintaining healthy circulation, which is essential for cognitive health. These fats support heart health by reducing bad cholesterol levels and improving blood flow to the brain.


Proper circulation ensures neurons receive oxygen and nutrients, reducing the risk of dementia-related mortality. Research associates daily olive oil consumption with a lower risk of cognitive decline, making it a beneficial alternative to other vegetable oils.

Key Nutrients in Olive Oil That Support Cognitive Health

Certain nutrients in olive oil provide direct benefits for brain function. These compounds help protect neurons, reduce oxidative stress, and improve memory, all contributing to a lower risk of dementia-related death.

Oleic Acid for Neuron Protection and Memory

Oleic acid, a primary monounsaturated fatty acid in olive oil, supports neuron function and may protect against cognitive decline. This healthy fat strengthens cell membranes, helping brain cells communicate efficiently. Research suggests that oleic acid contributes to memory retention and reduces dementia risk by protecting against neurodegeneration. Replacing other oils with extra virgin olive oil can improve diet quality and support long-term cognitive health.

Vitamin E’s Role in Reducing Dementia Risk

Vitamin E is an antioxidant that may help reduce oxidative stress, which is linked to brain cell damage. Studies show that higher vitamin E intake is linked to a reduced risk of dementia-related mortality.


This nutrient helps fight oxidative stress, a major contributor to neurodegeneration. Olive oil consumption provides a natural source of vitamin E, supporting brain function and lowering the risk of fatal dementia.

Polyphenols Crossing the Blood-Brain Barrier

Unlike many antioxidants, polyphenols in olive oil can cross the blood-brain barrier, allowing them to directly protect neurons. These compounds help prevent the accumulation of toxic proteins linked to dementia and support overall cognitive health.


Research associates higher polyphenol intake with a lower risk of death from dementia, highlighting their unique role in brain function. Including olive oil in a daily diet can help deliver these protective compounds to the brain.

Glowing neurons.

Replacing Unhealthy Fats with Olive Oil for Brain Health

Switching to olive oil instead of processed fats can improve diet quality and support brain health. Research suggests that replacing unhealthy fats with extra virgin olive oil has been linked to potential brain health benefits, such as supporting cognitive function.

Why Choose Olive Oil Over Margarine or Processed Fats?

Processed fats, such as margarine and hydrogenated oils, contain trans fats that contribute to inflammation and increase dementia risk. Olive oil, rich in monounsaturated fats and antioxidant compounds, provides a healthier alternative.


Benefits of Replacing Saturated Fats with Olive Oil


  • Supports cognitive health – Monounsaturated fats promote better blood flow to the brain.

  • Reduces inflammation – Olive oil intake helps lower markers of brain inflammation.

  • Improves heart health – Benefiting cardiovascular health reduces the risk of dementia-related mortality.

  • Enhances diet quality – Extra virgin olive oil contains polyphenols that protect neurons.

Olive Oil vs. Vegetable Oils for Brain Health

Other vegetable oils are often processed and lack the beneficial polyphenols in olive oil. Choosing extra virgin olive oil over vegetable oils can provide greater cognitive benefits.


Comparison

Olive Oil

Vegetable Oils

Healthy Fats

Rich in monounsaturated fats 

Often high in omega-6 fatty acids

Antioxidants  

Contains polyphenols and vitamin E

Minimal antioxidants

Inflammation  

Helps reduce inflammation

May contribute to inflammation

Brain Health Benefits

Linked to lower dementia risk

No strong link to dementia prevention

Simple Ways to Switch to Olive Oil in Your Diet

Replacing processed fats with olive oil daily can be an easy step toward better brain health. Small substitutions in cooking and meal preparation can make a big difference.


Easy Substitutions in Everyday Cooking


  • Use olive oil instead of butter when sautéing vegetables.

  • Replace commercial mayonnaise with olive oil-based dressings.

  • Swap margarine for olive oil when baking.

  • Choose extra virgin olive oil instead of processed vegetable oils for salad dressings.

Rolls of margarine/butter.

How Much Olive Oil Should You Consume to Help Prevent Dementia?

Daily olive oil consumption may offer brain-protective benefits, but finding the right amount is essential. Research suggests that moderate intake can lower the risk of dementia-related death.

Recommended Daily Amounts for Brain Health

Consuming about half a tablespoon of olive oil daily has been linked to a lower risk of fatal dementia. Studies from the Nurses’ Health Study and Harvard T.H. Chan School of Public Health found that individuals with regular olive oil intake had better cognitive-related health. Following dietary guidelines that include olive oil can support heart and brain function over time.

Is Extra Virgin Olive Oil the Best Choice?

Extra virgin olive oil contains high levels of antioxidant compounds and monounsaturated fatty acids, which may be beneficial for brain health. Unlike refined olive oil, extra virgin varieties retain polyphenols that support heart health and cognitive function. Choosing high-quality olive oil over other oils ensures greater protection against oxidative stress and inflammation.

Can Olive Oil Supplements Provide the Same Benefits?

Whole olive oil provides a complex mix of beneficial compounds that supplements cannot fully replicate. While some olive oil supplements contain polyphenols or monounsaturated fats, they lack the synergy of nutrients found in extra virgin olive oil. Research associates daily olive oil consumption with a lower risk of dementia, emphasizing the importance of including it in a healthy diet rather than relying on supplements alone.

Practical Tips for Adding Olive Oil to Your Diet

Adding olive oil to daily meals is simple and can enhance flavor and nutrition. Using it in various ways ensures consistent intake and potential brain health benefits.

Drizzling on Salads and Roasted Vegetables

Olive oil is commonly used as a dressing for fresh greens and roasted vegetables. Drizzling extra virgin olive oil over salads provides a source of monounsaturated fats and antioxidant compounds that support cognitive function. Using it as a base for homemade vinaigrettes helps improve diet quality while avoiding processed dressings.

Cooking Tips to Retain Olive Oil’s Nutrients

Heating olive oil at high temperatures can degrade some of its beneficial compounds. To preserve antioxidants, use olive oil for low to medium-heat cooking, such as sautéing or roasting at moderate temperatures. Storing olive oil in a cool, dark place prevents oxidation and helps maintain its brain-supporting properties.

Pairing Olive Oil with Other Brain-Boosting Foods

Combining olive oil with nutrient-rich foods enhances its effects on brain health. The Mediterranean diet, which emphasizes olive oil intake, includes several ingredients known for their cognitive benefits.


Combining with Nuts, Leafy Greens, and Fish


  • Nuts – Almonds and walnuts provide additional monounsaturated fats and vitamin E.

  • Leafy greens – Spinach and kale contain antioxidants that complement olive oil’s polyphenols.

  • Fatty fish – Salmon and sardines offer omega-3s that work alongside olive oil to support brain function.


Adding olive oil to a well-balanced diet has been linked to potential cognitive health benefits.

Up Your Olive Oil Consumption to Prevent the Risk of Dementia-Related Diseases

Incorporating olive oil into your diet may support brain health and lower the risk of dementia-related mortality. Research suggests that replacing processed fats with extra virgin olive oil, rich in monounsaturated fats and antioxidant compounds, can benefit cognitive function.


Simple changes, such as using olive oil instead of margarine or drizzling it over vegetables, can enhance diet quality and support heart health. Following dietary guidelines that emphasize olive oil intake as part of a healthy diet may provide long-term protection against cognitive decline.

Frequently Asked Questions

Can olive oil help prevent dementia?

Studies suggest that regular olive oil consumption is associated with a lower risk of dementia-related death and cognitive decline.

How much olive oil should I consume for brain health?

Consuming about half a tablespoon of olive oil daily has been associated with potential cognitive health benefits.

What types of olive oil are best for dementia prevention?

Extra virgin olive oil is the best choice, as it contains the highest levels of polyphenols and monounsaturated fatty acids that support brain health.

How does olive oil compare to other fats for brain health?

Olive oil, particularly extra virgin, offers more cognitive benefits than processed vegetable oils or saturated fats due to its anti-inflammatory and antioxidant properties.

Are there specific compounds in olive oil that support cognition?

Yes, polyphenols, vitamin E, and oleic acid in olive oil help protect neurons, reduce inflammation, and support overall cognitive function.

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Medically Reviewed By

Dr. James Pendleton

Dr. James Pendleton is a primary care physician specializing in a naturopathic approach to family medicine. He has nurtured a family practice in Seattle, directed a VIP medical center in Abu Dhabi, published several books and scientific articles, and designed innovative nutritional supplements for manufacturers worldwide.