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Melatonin vs. Valerian Root: Which Sleep Aid is Right for You?

Written by: Dr James Pendleton

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Published

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Time to read 10 min

Melatonin and valerian root are two natural sleep aids commonly used to improve sleep quality and treat insomnia. Melatonin is a naturally occurring hormone that regulates the sleep-wake cycle, while valerian root is an herbal supplement known for its relaxing effects on the nervous system. Both melatonin and valerian root work differently to help people fall asleep faster and stay asleep.


This article explores the key differences, benefits, and recommended usage of these sleep supplements to help determine which option improves sleep problems and maintains a healthy sleep cycle.

What is Melatonin and How Does It Work?

Melatonin is a naturally occurring hormone produced by the brain to regulate the body's internal clock and circadian rhythm. Melatonin levels rise in the evening, signaling the body to prepare for sleep and decrease in the morning to promote wakefulness.


This natural hormone is key in maintaining a healthy sleep-wake cycle, helping people fall asleep faster and stay asleep throughout the night. Sleep disturbances, poor sleep, and exposure to artificial light can disrupt melatonin production, leading to sleep problems and difficulty falling asleep.

Illustration of the brain

How Melatonin Supplements Help with Sleep

Melatonin supplements are commonly used to support the body's natural melatonin production and improve sleep quality. These sleep supplements mimic the effects of the hormone, making them a good sleep aid for those struggling with trouble sleeping.


Melatonin is commonly used to help adjust to time zone changes and shift work schedules. Melatonin supplements are often used by those experiencing occasional sleep disturbances, including older adults and individuals taking medications that may affect sleep cycles.

Person taking a melatonin supplement.

"Both melatonin and valerian root work differently to help people fall asleep faster and stay asleep.”

What is Valerian Root and How Does It Work?

Valerian root is an herbal remedy often used as a natural sleep aid. This dietary supplement is known for its calming properties and has been used in alternative medicine for centuries to promote relaxation and improve sleep quality.


Valerian root is traditionally used to support relaxation, which may contribute to better sleep. Many use valerian root for sleep as a natural alternative to prescription medications for treating insomnia and other sleep issues.

How Valerian Root Affects the Nervous System

Valerian root is believed to have calming properties that may support relaxation and sleep. This natural sleep aid interacts with neurotransmitters in the brain to promote a calming effect, making it easier to fall asleep and stay asleep.


Both valerian root and melatonin are used for sleep support, but valerian root is often taken consistently over time for its gradual calming effects. Traditionally used in complementary medicine, valerian root is considered one of the most effective alternative treatments for sleep disorders and mental health concerns related to stress and anxiety.

A close-up of valerian root in its natural dried form.

Melatonin vs. Valerian Root: Key Differences

Melatonin and valerian root are two natural sleep aids, but they work in different ways to improve sleep quality. Understanding their effects can help determine which sleep supplement is best for treating insomnia, sleep disturbances, and other sleep issues.

How They Affect Sleep Quality

Melatonin supplements support the body’s internal clock, which may help signal when it’s time to sleep. This makes melatonin a good sleep aid for resetting circadian rhythms, especially for those experiencing jet lag or shift work sleep disorder.


Valerian root works by calming the nervous system, reducing anxiety, and promoting relaxation, which helps with falling asleep and staying asleep. While melatonin primarily influences sleep-wake cycles, valerian root appears to improve overall sleep quality by reducing stress-related sleep problems.

Onset of Action: Which Works Faster?

Melatonin supplement effects typically begin within 30 to 60 minutes, making it useful for those who need help falling asleep quickly. Valerian root works more gradually, often taking a few weeks of regular use to reach full effectiveness. People looking for immediate results may find melatonin more effective, while those seeking long-term relaxation benefits may prefer valerian root for sleep.

Which is Better for Long-Term Use?

Melatonin is considered safe for short-term use, but long-term effects on natural hormone production are still being studied. Valerian root is often used long-term for relaxation, but some individuals report temporary discomfort when discontinuing use. Both valerian and melatonin are effective sleep aids, but valerian root may be the better choice for those seeking a long-term sleep supplement without affecting melatonin levels.

A bowl of supplements.

Dosages and Side Effects of Melatonin and Valerian Root

When taking melatonin or valerian root, proper dosage and awareness of potential side effects are essential. Understanding recommended dosages can help avoid sleep problems and minimize drug interactions with certain prescription medications or other sleep aids.

Melatonin Dosage Guide

Melatonin dosage depends on the sleep issue being treated. Lower doses are typically recommended for mild sleep problems, while higher amounts may be used for conditions like jet lag.


  • Occasional sleep troubles: 0.5 to 3 mg, taken 30-60 minutes before bedtime.

  • Jet lag: 2 to 5 mg before bedtime in the new time zone.

  • Chronic insomnia: 3 to 10 mg, under medical supervision.


Common side effects of melatonin supplements include:


  • Grogginess in the morning

  • Vivid dreams or nightmares

  • Dizziness or headaches

  • Nausea

  • Changes in circadian rhythms with prolonged use

Valerian Root Dosage Guide

Valerian root is commonly taken as a tea, capsule, or liquid extract. The recommended dosage varies based on the form and individual needs.



Potential side effects of valerian root include:


  • Dizziness or drowsiness

  • Stomach upset

  • Dry mouth

  • Headaches

  • Withdrawal symptoms if stopped suddenly after long-term use

Can You Take Melatonin and Valerian Root Together?

Combining melatonin and valerian root may enhance relaxation and sleep quality, but combining both supplements can increase drowsiness and dizziness. These two natural sleep aids work differently, and their effects may overlap, leading to stronger sedative effects. To avoid possible interactions, people taking other medications should consult a healthcare provider before combining valerian root and melatonin.

A bowl of dried valerian root.

Melatonin Supplements vs. Valerian Root: Who Should Use Which?

Choosing between melatonin supplements and valerian root depends on the cause of sleep disturbances. Some people need help adjusting their sleep cycle, while others struggle with stress-related insomnia.

Best Option for Occasional Sleep Problems

Melatonin is a good sleep aid for those experiencing temporary sleep issues, such as adjusting to a new time zone or recovering from shift work sleep disorder. This natural hormone helps regulate the body's internal clock, making it easier to fall asleep faster and reset circadian rhythms. Taking melatonin before bed can support a smooth transition to a new sleep-wake cycle without long-term reliance.

Best Option for Anxiety-Related Insomnia

Valerian root is a better option for those whose sleep problems stem from anxiety or stress. This herbal supplement calms the nervous system, promotes relaxation, and improves sleep quality. People with trouble sleeping due to racing thoughts or stress-related sleep disturbances may find valerian root for sleep more effective than melatonin. Its relaxing effects can also benefit those experiencing mild mental health concerns.

Who Should Avoid Each Supplement?

People taking sedatives, blood pressure medications, or antidepressants should consult a healthcare provider before using melatonin or valerian root. Melatonin may interact with blood pressure medications, antidepressants, and other medications that affect circadian rhythms.


Valerian root may cause drowsiness when combined with sedatives, alcohol, or other sleep aids. Pregnant women, individuals with liver conditions, and those with sleep disorders requiring medical treatment should consult a healthcare provider before taking valerian root or melatonin supplements.

Melatonin IR vs. Valerian Root for Relaxation

Immediate-release (IR) melatonin and valerian root help with relaxation, but they work differently. Melatonin IR quickly signals the body that it is time to sleep, making it useful for falling asleep faster. Valerian root works by gradually reducing nervous system activity, promoting a steady feeling of calm.


Those seeking a sleep supplement to help with general relaxation before bed may prefer valerian root, while melatonin IR is better for resetting circadian rhythms.

How to Choose the Right Type of Melatonin

Melatonin supplements are available in immediate-release (IR) and extended-release (XR) forms. IR melatonin helps people fall asleep quickly, while XR melatonin supports staying asleep longer. Choosing the right type depends on individual sleep problems.


Melatonin Type

Best For

How It Works

Immediate-Release (IR)

Trouble falling asleep

Absorbs quickly into the bloodstream

Extended-Release (XR)

Staying asleep through the night

Releases melatonin gradually over time

Are There Other Natural Sleep Aids to Consider?

Aside from melatonin and valerian root, other natural sleep aids may improve sleep quality and relaxation. Herbal supplements like chamomile and passionflower have calming effects, while minerals like magnesium support the body's internal clock. These alternative treatments can be used alone or with sleep supplements to promote a good night's sleep.

Chamomile vs. Melatonin

Chamomile is a traditional herb known for its relaxing effects, making it useful for unwinding before bed. Unlike melatonin, which directly influences circadian rhythms,  chamomile works by easing stress and mild anxiety , leading to better sleep. People who struggle with sleep due to tension or restlessness may find chamomile tea a helpful alternative to melatonin supplements.

Valerian Root vs. Kava for Anxiety Relief

Both valerian root and kava are used in complementary medicine for relaxation, though kava has been associated with potential liver health concerns. While valerian root appears to work by calming the nervous system gradually, kava has stronger sedative effects that can reduce anxiety more quickly.


Supplement

Best For

How It Works

Valerian Root

Mild stress-related sleep issues

Increases relaxation over time

Kava 

Stronger anxiety relief

Acts as a sedative, reducing anxiety quickly


People looking for a natural sleep aid that gently promotes relaxation may prefer valerian root, while kava may be a better choice for those needing stronger anxiety relief.

A cup of chamomile tea.

Choosing the Right Sleep Aid for Your Needs

Melatonin and valerian root are two natural sleep aids that support better sleep but work differently. Melatonin supplements help regulate circadian rhythms, making them ideal for jet lag and shift work sleep disorder, while valerian root promotes relaxation and reduces anxiety-related sleep disturbances.


Dosages vary, with melatonin typically used in smaller amounts for short-term sleep issues and valerian root taken in moderate doses for ongoing relaxation support. Both sleep supplements can be effective, but the best choice depends on individual sleep challenges. Trying the option that aligns with personal sleep goals and consulting a healthcare provider if needed ensures safe and effective use.

Frequently Asked Questions

Can I take valerian root and melatonin together for better sleep?

Yes, but combining them may increase drowsiness, so use caution and consult a doctor if taking other medications.

What’s the safest dosage of melatonin for long-term use?

Low doses of 0.5 mg to 3 mg are generally considered safe, but extended use should be monitored by a healthcare provider.

How long does valerian root stay in your system?

Valerian root can stay in the system for about 4 to 6 hours, but its calming effects may last longer with regular use.

Which is better for insomnia: melatonin or valerian root?

Melatonin is better for sleep-wake cycle issues, while valerian root is more effective for anxiety-related insomnia.

Can children or teenagers use valerian root or melatonin safely?

Melatonin may be safe in low doses for children under medical supervision, but valerian root is not widely recommended for younger users.

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Medically Reviewed By

Dr. James Pendleton

Dr. James Pendleton is a primary care physician specializing in a naturopathic approach to family medicine. He has nurtured a family practice in Seattle, directed a VIP medical center in Abu Dhabi, published several books and scientific articles, and designed innovative nutritional supplements for manufacturers worldwide.